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The protection and efficacy of sildenafil with the therapy of PAH in small children beneath 1 yr of age hasn't been set up as no information is offered .
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When Employed in pulmonary arterial hypertension sufferers, nonetheless, the oral bioavailability of sildenafil after a dosing regimen of eighty mg 3 times a day, was on normal forty three% higher than in comparison to the lower doses .
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Because of the lack of knowledge to the influence of sildenafil indicated to the therapy of pulmonary arterial hypertension (PAH) in pregnant Women of all ages, sildenafil will not be advisable for Ladies of childbearing opportunity Unless of course also using appropriate contraceptive steps .
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